InterXClinic InterX Overview

Working Hours

Monday - Friday: 9.00am – 5:30pm
105-107 Bath Road
Cheltenham GL53 7LE
Tel.: +44(0)1242 210 954


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InterX is a medical device that uses electrical stimulation for relief of acute and chronic pain. The device is unusual in that it incorporates a feedback system that modulates the electrical stimulus in response to the impedance of the patient’s skin.

Interactive Neurostimulation therapy comprises a unique ability to locate the optimal treatment areas with the InterX, targeting them with specific interactive, high amplitude, high density pulsing current. Cutaneous stimulation does not cause muscular contraction and the InterX is safe to use over internal metal work.

The design of the flexible array electrodes ensures that most treatment is delivered to areas of low impedance. The low impedance on the skin is caused by an increase in the sympathetic skin response and research shows that these points correlate to myofascial trigger points1 and major nerve branches2.

The device generates high amplitude, high density current and damped biphasic electrical impulses that are delivered to the tissue via a set of electrode pads placed directly to the skin surface at the required area, thus enabling stimulation of all cutaneous nerve endings which in return triggers the bodies response with a number of pain relieving mechanisms. The InterX is sensitive to changes in skin impedance, where electro-physiology of the skin and underlying tissues controls output from the device by varying the voltage in order to maintain a constant peak current.

The InterX is a Class II medical device. It is a portable handheld unit that is powered by standard AA batteries. It is easy to use, and has no known adverse side effects that are commonly seen following the use of medications. There is no electrode gel required. The InterX produces a pulsing current ranging from 15 – 480 pulses per second. The research shows that low frequency stimulation causes a release of endomorphin, beta-endorphin and enkephalins where a high frequency stimulation releases dynorphins3. The broad range of pulsation by the InterX ensures that all types of endorphines are released.

InterX therapy has been reported to provide non-drug pain relief; increases range of motion and a reduction in swelling in acute injuries4 5

To summarise, a new treatment modality InterX is clinically proven to be consistently effective at getting patients back into active rehabilitation sooner, with less pain and more ROM6. The InterX has shown to be highly effective across a wide range of conditions, helping a broad spectrum of patients return to an active lifestyle.

  • Main features include:
  • Non-invasive
  • Safe
  • No side effects
  • Nociceptive and Neuropathic pain
  • Speeds up the recovery time
  • Can be used when patient non responsive or intolerant to pain medication

Available clinical data includes peer-review publications with controlled study demonstrating:

  • PAIN reduction
  • OEDEMA reduction
  • RECOVERY TIME reduction
  • ROM increase


  1. Schultz et al. The evaluation of electrodermal activities in the identification of myofascial trigger points: Arch Phys Med Rehabil Vol 88, June 2007
  2. Korr I: Cutaneous patterns of sympathetic activity in clinical abnormalities of the musculoskeletal system, 1964
  3. Han J S, Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies.
  4. Maale G: The effect of the InterX 5000 on pain reduction in the severe chronic orthopedic patient. International congress of technology in arthroplasty, Kyoto, 2005
  5. Coleman S. Knee Injuries – InterX therapy to solve unresolved sport injuries [presentation]. International Congress on Sports Rehabilitation and Traumatology, Bologna, Italy, 2005.
  6. Gorodetski I G, Gorodnichenko A I, Tursin P S, Reshetnyak V K, Uskov, O N: Non-invasive interactive Neurostimulation in the post-operative recovery of patients with a trochanteric fracture of the femur. Journal of Bone and Joint Pain (Br), Nov. 2007