Research article Non-invasive interactive neurostimulation (InterX ™) reduces acute pain in patients following total knee replacement surgery: a randomised, controlled trial Ashok K Nigam1, Drena M Taylor1 and Zulia Valeyeva2* * Corresponding author: Zulia Valeyeva zuliaf@interxclinic.com Author Affiliations 1 Prince Philip Hospital, Carmarthenshire NHS Trust, Mawr Dafen, Llanelli, UK 2 InterX Clinic Cheltenham, Maple House, Bayshill Rd, Cheltenham, Glouc, UK Journal of Orthopaedic Surgery and Research 2011, 6:45 doi:10.1186/1749-799X-6-45   The electronic version of this article is the complete one and can be found online at: http://www.josr-online.com/content/6/1/45 Received: 27 October 2010 Accepted: 24 August 2011 Published: 24 August 2011 © 2011 Nigam et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.   Abstract Background Adequate post-operative pain relief following total knee replacement (TKR) is very important to optimal post-operative recovery. Faster mobilisation and rehabilitation ultimately results in optimum recovery outcomes, but pain is often the limiting factor. This study evaluates the potential clinical benefit of the InterX neurostimulation device on pain reduction and rehabilitative outcome. Methods A clinical trial under [...]

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